Hunt-Hess

Hunt and Hess clinical grading of aneurysmal subarachnoid hemorrhage

Time-stamped bedside clinical grade for the presenting condition after aneurysmal subarachnoid hemorrhage. It is not derived from CT blood burden, is vulnerable to examination confounding and supplies communication/prognostic context rather than a grade-only treatment algorithm.

vigenteHunt and Hess / neurosurgical practice1968 five-grade scale; 2023 AHA/ASA care context1968Clinical

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Categorias

Reescritas a partir da fonte e citadas
1
1 de 5

Grade 1

At a documented clinical assessment time after aneurysmal subarachnoid hemorrhage, the patient is asymptomatic or has only mild headache and at most slight nuchal rigidity, remains alert, and has no focal neurologic deficit. This is a bedside clinical grade and cannot be inferred from a small CT blood burden.

CondutaTreat confirmed aneurysmal SAH as a neurovascular emergency even at grade 1 and follow current aneurysm-securing, rebleeding-prevention and neurocritical pathways. The grade communicates clinical state but does not choose clipping versus coiling, blood-pressure targets, nimodipine, monitoring intensity or disposition by itself.
RiscoGrade 1 is the least impaired canonical clinical category, but it does not mean benign disease. In one 1,200-patient single-center spontaneous-SAH cohort from 1996-2009, in-hospital mortality was 3 percent for grades 1 and 2 combined; that historical combined figure is not an individual estimate or a grade-1-specific current rate.
verificadoSurgical risk as related to time of intervention in the repair of intracranial aneurysmsHunt and Hess 1968, DOI 10.3171/jns.1968.28.1.0014, grade I clinical definition; Hoh et al. 2023, DOI 10.1161/STR.0000000000000436, current aSAH care context; Lantigua et al. 2015, PMC4556224, Abstract and Table 2 for combined grade 1-2 cohort mortality.
2
2 de 5

Grade 2

The patient is alert with moderate-to-severe headache and nuchal rigidity and has no neurologic deficit other than a possible cranial-nerve palsy. Drowsiness/confusion moves the state toward grade 3; a non-cranial focal deficit conflicts with canonical grade 2 and should be exposed rather than hidden.

CondutaGrade 2 still requires the full emergency aneurysmal-SAH pathway and definitive aneurysm assessment/management. Use the time-stamped examination with aneurysm, hydrocephalus, rebleeding, CT blood burden and systemic data; do not convert grade 2 into a treatment shortcut.
RiscoPopulation prognosis is generally more favorable than in poor-grade SAH, but grade 2 is not low risk in isolation. The cited 1,200-patient cohort reported 3 percent in-hospital mortality for grades 1-2 combined, not separately, and cannot provide a contemporary personal forecast.
verificadoSurgical risk as related to time of intervention in the repair of intracranial aneurysmsHunt and Hess 1968, DOI 10.3171/jns.1968.28.1.0014, grade II definition including possible cranial-nerve palsy; Hoh et al. 2023 AHA/ASA guideline; Lantigua et al. 2015, PMC4556224, cohort methods/results.
3
3 de 5

Grade 3

The time-stamped examination shows drowsiness or confusion and/or a mild focal neurologic deficit. Document consciousness, orientation, motor findings, Glasgow Coma Scale and any sedation, seizure, hydrocephalus, hypoxia or other confounder instead of recording only the numeral.

CondutaUrgently evaluate and treat the aneurysmal SAH and reversible contributors to deterioration, including hydrocephalus, rebleeding, seizure and physiologic disturbance, under current neurovascular/neurocritical guidance. Hunt-Hess 3 alone does not specify an aneurysm procedure or forecast response.
RiscoGrade 3 indicates an impaired clinical state and is associated with worse population outcomes than grades 1-2. The historical single-center cohort reported 9 percent in-hospital mortality for grade 3, but age, GCS, CT burden, aneurysm factors, complications and care decisions materially affect outcome, so the number must not be individualized.
verificadoSurgical risk as related to time of intervention in the repair of intracranial aneurysmsHunt and Hess 1968, DOI 10.3171/jns.1968.28.1.0014, grade III definition; Lantigua et al. 2015, PMC4556224, Abstract, Methods and multivariable mortality findings; Hoh et al. 2023 AHA/ASA guideline for current management.
4
4 de 5

Grade 4

The patient is stuporous with moderate-to-severe hemiparesis and may have early decerebrate rigidity and vegetative disturbance. Distinguish stupor from deep coma and record whether sedation, intubation, paralysis or another reversible factor prevents a valid examination.

CondutaGrade 4 is poor-grade SAH requiring immediate specialist neurovascular and neurocritical evaluation, investigation of reversible causes and patient-specific aneurysm treatment planning. It is not a futility category and must not independently trigger non-intervention or withdrawal of life support.
RiscoSevere neurologic impairment carries substantial population risk. A 1996-2009 single-center spontaneous-SAH cohort reported 24 percent in-hospital mortality for grade 4, but this is a cohort-specific historical association affected by subsequent complications and treatment-limitation decisions, not an individual probability.
verificadoSurgical risk as related to time of intervention in the repair of intracranial aneurysmsHunt and Hess 1968, DOI 10.3171/jns.1968.28.1.0014, grade IV definition; Hoh et al. 2023, DOI 10.1161/STR.0000000000000436, patient-centric current care; Lantigua et al. 2015, PMC4556224, mortality and mode-of-death analyses.
5
5 de 5

Grade 5

The patient is in deep coma with decerebrate rigidity and appears moribund or has failing vital centers on the contemporaneous examination. Assign only from a reliable clinical state; if sedatives, neuromuscular blockade, intubation or postictal suppression obscure the examination, return confounded rather than assuming grade 5.

CondutaGrade 5 demands immediate expert evaluation, resuscitation and assessment of reversible factors and aneurysm-treatment options under current guidance. The category alone cannot establish irreversibility, deny intervention, determine goals of care or justify withdrawal of life-sustaining treatment.
RiscoGrade 5 is the most impaired canonical clinical state and has the worst population prognosis, yet survivors exist and the grade is not deterministic. The cited historical cohort reported 71 percent in-hospital mortality, with many deaths involving brain death or withdrawal decisions; use this only as cohort context, never a personal probability or futility threshold.
verificadoSurgical risk as related to time of intervention in the repair of intracranial aneurysmsHunt and Hess 1968, DOI 10.3171/jns.1968.28.1.0014, grade V definition; Hoh et al. 2023 AHA/ASA guideline for current care; Lantigua et al. 2015, PMC4556224, grade-specific mortality and mode-of-death results.
Lógica de decisão estruturada

Grade a real, time-stamped clinical examination only. Keep CT blood burden separate, expose confounders and uncertainty, and never translate a poor Hunt-Hess grade into autonomous treatment limitation or futility.

{
  "categories": [
    {
      "outcome_code": "1",
      "consciousness": "alert",
      "headache": "absent_or_mild",
      "nuchal_rigidity": "absent_or_slight",
      "focal_deficit": "absent"
    },
    {
      "outcome_code": "2",
      "consciousness": "alert",
      "headache": "moderate_to_severe",
      "nuchal_rigidity": "present",
      "focal_deficit": "none_except_possible_cranial_nerve_palsy"
    },
    {
      "outcome_code": "3",
      "consciousness": "drowsy_or_confused",
      "headache": "not_category_defining",
      "nuchal_rigidity": "not_category_defining",
      "focal_deficit": "none_or_mild"
    },
    {
      "outcome_code": "4",
      "consciousness": "stupor",
      "headache": "not_assessable_or_not_category_defining",
      "nuchal_rigidity": "not_category_defining",
      "focal_deficit": "moderate_to_severe_hemiparesis_possible_early_decerebrate_rigidity_and_vegetative_disturbance"
    },
    {
      "outcome_code": "5",
      "consciousness": "deep_coma",
      "headache": "not_assessable",
      "nuchal_rigidity": "not_category_defining",
      "focal_deficit": "decerebrate_rigidity_with_moribund_appearance_or_failing_vital_centers"
    }
  ],
  "applicability": {
    "intended_use": "Describe the bedside clinical condition of a patient with ruptured aneurysmal subarachnoid hemorrhage at a defined timepoint.",
    "required_input": "Direct neurologic examination including level of consciousness, orientation, meningeal symptoms/signs, cranial nerves and focal motor deficit.",
    "not_an_imaging_scale": "Do not derive Hunt-Hess from CT, CTA, MRI or angiography. CT blood burden and intraventricular hemorrhage belong in a radiologic scale such as modified Fisher and are reported separately.",
    "outside_scope": [
      "unruptured_aneurysm_risk",
      "nonaneurysmal_headache_without_SAH",
      "CT_blood_burden",
      "delayed_cerebral_ischemia_diagnosis",
      "standalone_long_term_outcome_prediction",
      "treatment_selection_by_grade_alone"
    ]
  },
  "assessment_time_and_provenance": {
    "preferred_timepoint": "Record the grade at admission or another explicitly named time after initial stabilization; never mix findings from different examinations into one grade.",
    "required_provenance": [
      "assessment_datetime",
      "examiner_or_source_note",
      "before_or_after_airway_and_sedating_medication",
      "Glasgow_Coma_Scale_when_available",
      "neurologic_change_since_prior_exam"
    ],
    "trajectory_rule": "Store serial grades with their timestamps. A later grade must not overwrite the admission state or conceal deterioration or improvement."
  },
  "confounder_gate": {
    "potentially_invalidating": [
      "sedation",
      "general_anesthesia",
      "intubation_without_reliable_pre_intubation_exam",
      "neuromuscular_blockade",
      "postictal_state",
      "active_seizure",
      "intoxication",
      "major_metabolic_derangement",
      "hypoxia_or_hypotension",
      "severe_analgesic_effect",
      "language_or_hearing_barrier"
    ],
    "disease_mediated_but_important": [
      "acute_hydrocephalus",
      "large_intraparenchymal_hematoma",
      "rebleeding",
      "raised_intracranial_pressure"
    ],
    "rule": "If consciousness or motor findings cannot be attributed reliably to the SAH clinical state, return grade indeterminate/confounded and preserve the observed examination plus cause; do not manufacture a grade."
  },
  "grading_algorithm": [
    {
      "step": 1,
      "state": "deep_coma_with_decerebrate_rigidity_and_moribund_or_failing_vital_centers",
      "output": "5"
    },
    {
      "step": 2,
      "state": "stupor_with_moderate_to_severe_hemiparesis_with_possible_early_decerebrate_rigidity_or_vegetative_disturbance",
      "output": "4"
    },
    {
      "step": 3,
      "state": "drowsiness_or_confusion_with_or_without_mild_focal_deficit",
      "output": "3"
    },
    {
      "step": 4,
      "state": "alert_with_moderate_to_severe_headache_and_nuchal_rigidity_and_no_deficit_other_than_possible_cranial_nerve_palsy",
      "output": "2"
    },
    {
      "step": 5,
      "state": "asymptomatic_or_alert_with_mild_headache_and_at_most_slight_nuchal_rigidity_and_no_deficit",
      "output": "1"
    },
    {
      "step": 6,
      "state": "features_do_not_fit_one_grade_or_required_exam_is_missing",
      "output": "indeterminate_or_adjacent_grade_range"
    }
  ],
  "boundary_rules": {
    "grade_1_2": "Moderate/severe headache plus definite nuchal rigidity supports grade 2; mild headache and at most slight rigidity supports grade 1. A cranial-nerve palsy may still be grade 2 but any non-cranial focal deficit does not fit grade 2.",
    "grade_2_3": "Drowsiness or confusion moves the patient beyond grade 2 even when focal deficit is absent. An alert patient with a mild non-cranial focal deficit does not cleanly fit canonical grade 2 and should not be forced without documenting the conflict.",
    "grade_3_4": "Drowsiness/confusion and at most mild focal deficit is grade 3; stupor or moderate/severe hemiparesis is grade 4.",
    "grade_4_5": "Stupor with severe deficit is grade 4; deep coma with established decerebrate rigidity and moribund/failing-vital-center appearance is grade 5.",
    "worst_feature_rule": "Use the poorest defensible category-defining clinical feature at the same assessment time, while retaining all observed findings and confounders.",
    "discordance_rule": "When consciousness and motor severity point to nonadjacent grades, report the discordance and seek reassessment rather than averaging the grade."
  },
  "historical_variant_boundary": {
    "systemic_or_vasospasm_modifier": "Historical formulations add one grade for serious systemic disease or severe angiographic vasospasm. Because definitions and modern application vary, apply this only when the reporting protocol explicitly requests the original modifier, store the unmodified clinical grade, name the modifier and never exceed grade 5.",
    "grade_0_and_1a": "Some extended tables include grade 0 for an unruptured aneurysm and grade 1a for a fixed neurologic deficit without acute meningeal/brain reaction. They are outside this canonical 1-5 outcome set and must be identified as variants, not silently mapped to grade 1 or 2."
  },
  "clinical_and_management_context": {
    "emergency_rule": "Suspected or confirmed aneurysmal SAH requires emergency neurovascular and neurocritical management regardless of Hunt-Hess grade.",
    "treatment_rule": "The grade does not decide aneurysm securing, clipping versus coiling, blood-pressure strategy, nimodipine, hydrocephalus treatment, seizure care, delayed-cerebral-ischemia surveillance or ICU intensity by itself.",
    "current_context": "Use current AHA/ASA aneurysmal-SAH guidance together with aneurysm status, rebleeding risk, hydrocephalus/ICP, cerebral ischemia, systemic complications, age, baseline function and goals of care.",
    "poor_grade_not_futility": "Grades 4 and 5 denote a poor initial clinical state but are not a declaration of futility and must not autonomously trigger treatment limitation or withdrawal of life support."
  },
  "prognosis_and_reliability": {
    "direction": "Higher grade is associated with worse outcomes at the population level, but the scale is ordinal and does not yield a calibrated individual probability.",
    "cohort_example": "In one prospective single-center cohort of 1,200 consecutive spontaneous SAH patients enrolled from 1996-2009, in-hospital mortality was 3 percent for grades 1-2 combined, 9 percent for grade 3, 24 percent for grade 4 and 71 percent for grade 5.",
    "cohort_caveat": "Those figures reflect one historical-center cohort, included spontaneous aneurysmal and nonaneurysmal SAH, and were affected by subsequent complications and life-support decisions. They are context, not a bedside forecast or current benchmark.",
    "interobserver_evidence": "In a 50-patient, 103-paired-assessment study, Hunt-Hess had weighted kappa 0.48 (95% CI 0.36-0.59), lower than WFNS 0.60 and PAASH 0.64; subjective terms therefore require explicit examination provenance.",
    "complementary_data": "Report GCS and, when relevant, WFNS/PAASH, age, baseline status, modified Fisher/CT findings, aneurysm features and systemic physiology rather than treating Hunt-Hess as a complete prognostic model."
  },
  "agent_output_contract": [
    "exact_Hunt_Hess_grade_or_indeterminate_state",
    "assessment_datetime_and_pre_or_post_intervention_context",
    "consciousness_orientation_headache_nuchal_rigidity_cranial_nerve_and_motor_findings",
    "GCS_when_available",
    "all_examination_confounders",
    "separate_modified_Fisher_or_other_imaging_grade_if_available",
    "serial_trajectory_without_overwriting_prior_grade",
    "urgent_aSAH_context_without_grade_only_treatment_or_futility_claim"
  ],
  "missing_input_behavior": [
    "If there is no direct or reliably documented clinical examination, do not infer Hunt-Hess from CT appearance; return clinical grade unavailable.",
    "If sedation, intubation or another confounder obscures the examination and no pre-confounder state exists, return confounded rather than grade 4 or 5.",
    "If headache/rigidity distinguish grades 1 and 2 but are undocumented, return 1-versus-2 unless another feature establishes a higher grade.",
    "If alertness versus drowsiness/confusion is unclear, retain 2-versus-3 uncertainty and request a time-stamped reassessment.",
    "If the patient changes clinically, create a new timepoint rather than retroactively changing the earlier grade."
  ],
  "supporting_sources": [
    {
      "role": "primary_scale",
      "citation": "Hunt and Hess. J Neurosurg. 1968;28:14-20",
      "doi": "10.3171/jns.1968.28.1.0014",
      "pmid": "5635959"
    },
    {
      "role": "current_care_context",
      "citation": "Hoh et al. Stroke. 2023;54:e314-e370",
      "doi": "10.1161/STR.0000000000000436",
      "pmid": "37212182"
    },
    {
      "role": "interobserver_reliability",
      "citation": "Degen et al. Stroke. 2011;42:1546-1549",
      "doi": "10.1161/STROKEAHA.110.601211",
      "pmid": "21527761"
    },
    {
      "role": "cohort_risk_context",
      "citation": "Lantigua et al. Crit Care. 2015;19:309",
      "doi": "10.1186/s13054-015-1036-0",
      "pmcid": "PMC4556224"
    }
  ],
  "source_locator": "Hunt and Hess 1968, DOI 10.3171/jns.1968.28.1.0014, pp. 14-20 for the original clinical categories and historical modifier; Hoh et al. 2023 AHA/ASA guideline, DOI 10.1161/STR.0000000000000436 for current aneurysmal-SAH management context; Degen et al. 2011 abstract/results for weighted kappa; Lantigua et al. 2015, PMC4556224, Abstract and Table 2 for cohort mortality and its determinants."
}

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